Benzyl L-leucyl-L-phenylalaninate (TFA)

Product Name:Benzyl L-leucyl-L-phenylalaninate (TFA)

Form:TFA salt

Purity:98%

Storage:-20^oC

Cas No:70637-28-4

Molar Mass:482.49

Chemical Formula:C24H29F3N2O5

Synonyms:benzyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoate;2,2,2-trifluoroacetic acid

IUPAC Name:benzyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoate;2,2,2-trifluoroacetic acid

SMILES:OC(C(F)(F)F)=O.O=C(OCC1=CC=CC=C1)[C@@H](NC([C@@H](N)CC(C)C)=O)CC2=CC=CC=C2

InChIKey:RIZSOQODQYBBID-FKLPMGAJSA-N

InChI:InChI=1S/C22H28N2O3.C2HF3O2/c1-16(2)13-19(23)21(25)24-20(14-17-9-5-3-6-10-17)22(26)27-15-18-11-7-4-8-12-18;3-2(4,5)1(6)7/h3-12,16,19-20H,13-15,23H2,1-2H3,(H,24,25);(H,6,7)/t19-,20-;/m0./s1

Sequence:LF

Reference:Johnson, H. W., Lowe, E., Anderl, J. L., Fan, A., Muchamuel, T., Bowers, S., ... & McMinn, D. L. (2018). Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S, 3 R)-N-((S)-3-(Cyclopent-1-en-1-yl)-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido) propanamido) propenamide). Journal of medicinal chemistry, 61(24), 11127-11143.