benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate

Product Name:benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate

Form:Free base

Purity:98%

Storage:-20^oC

Cas No:70637-26-2

Molar Mass:468.59

Chemical Formula:C27H36N2O5

Synonyms:benzyl (tert-Butoxycarbonyl)-L-leucyl-L-phenylalaninate

IUPAC Name:benzyl (2S)-2-[[(2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]-3-phenylpropanoate

SMILES:O=C([C@@H](NC([C@H](CC(C)C)NC(OC(C)(C)C)=O)=O)CC1=CC=CC=C1)OCC2=CC=CC=C2

InChIKey:IKZFNIAMQFYRSM-GOTSBHOMSA-N

InChI:InChI=1S/C27H36N2O5/c1-19(2)16-22(29-26(32)34-27(3,4)5)24(30)28-23(17-20-12-8-6-9-13-20)25(31)33-18-21-14-10-7-11-15-21/h6-15,19,22-23H,16-18H2,1-5H3,(H,28,30)(H,29,32)/t22-,23-/m0/s1

Sequence:LF

Reference:Johnson, H. W., Lowe, E., Anderl, J. L., Fan, A., Muchamuel, T., Bowers, S., ... & McMinn, D. L. (2018). Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S, 3 R)-N-((S)-3-(Cyclopent-1-en-1-yl)-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido) propanamido) propenamide). Journal of medicinal chemistry, 61(24), 11127-11143.