Product Name: CREBtide [KRREILSRRPSYR], 5-FAM labeled
Sequence One Letter Code: 5-FAM-KRREILSRRPSYR
Sequence Three Letter Code: 5-FAM-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH
Chemical Formula:C94H139N29O25
Molecular Weight: 2075.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C Protected from light
Source / Species: Human, mouse, rat, bovine, zebrafish
Conjugation: Conjugated
Conjugation Type: Fluorescent dyes
Code Nacres: NA.26
Application: 5-FAM CREBtide is a fluorescent synthetic peptide substrate derived from the phosphorylation site of cAMP response element-binding protein. It is selectively phosphorylated by protein kinase A, making it useful for quantifying PKA activity in fluorescence-based assay systems. The 5-FAM label enables direct and sensitive detection of phosphorylation-related assay outputs. 5-FAM CREBtide is widely used to study cAMP-dependent signaling pathways, transcriptional regulation, kinase activity, enzyme kinetics, and inhibitor screening. This peptide supports research into PKA-mediated cellular responses, phosphorylation-dependent signal transduction, and biochemical assay development for kinase pathway analysis.
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