CREBtide [KRREILSRRPSYR], Phosphorylated, C-term K

Product Name: CREBtide [KRREILSRRPSYR], Phosphorylated, C-term K

Sequence One Letter Code: KRREILSRRPS-pY-RK

Sequence Three Letter Code: H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-pTyr-Arg-Lys-OH

Chemical Formula:C79H142N31O23P

Molecular Weight: 1925.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Human, mouse, rat, bovine, zebrafish

Conjugation: Unconjugated

Code Nacres: NA.26

Application: CREBtide is a synthetic peptide substrate designed for protein kinase A activity assays and is based on the phosphorylation motif found in cAMP response element-binding protein. With a reported Km of 3.9 µM, CREBtide provides a reliable tool for evaluating PKA enzymatic activity in vitro. This peptide is widely used in biochemical studies of kinase signaling, cAMP-dependent pathways, phosphorylation-driven transcriptional regulation, and enzyme kinetics. CREBtide is especially useful for PKA inhibitor screening, kinase activity profiling, and investigations of PKA-mediated cellular signaling networks involved in growth, differentiation, metabolism, and gene expression.