RGD-4C

RGD-4C is a double cyclic peptide containing the Arg-Gly-Asp integrin-binding motif, engineered for high-affinity targeting of integrins expressed in tumor angiogenesis and inflamed synovial tissue. This peptide preferentially binds integrins such as αvβ3 and αvβ5, which are upregulated in neovascular and inflammatory environments. RGD-4C can be internalized into targeted cells, making it valuable for drug delivery research, tumor imaging, and integrin-targeted studies. It is widely used to investigate cell adhesion, migration, angiogenic signaling, tumor vascular targeting, and integrin-mediated cellular uptake.

Product Name: RGD-4C

Sequence One Letter Code: ACDCRGDCFCG (Disulfide bridge: 2-10 and 4-8)

Sequence Three Letter Code: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: 2-10 and 4-8)

Chemical Formula:C42H64N14O16S4

Molecular Weight: 1145.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: synthetic

Conjugation: Unconjugated

Code Nacres: NA.26