Spike protein SARS-CoV-2 sensitive substrate

Product Name: Spike protein SARS-CoV-2 sensitive substrate

Sequence One Letter Code: FAM-QTNSPRRARSVASQSK-QXL520™-NH2

Sequence Three Letter Code: 5-FAM-Gln-Thr-Asn-Ser-Pro-Arg-Arg-Ala-Arg-Ser-Val-Ala-Ser-Gln-Ser-Lys-(QXL® 520)-NH2

Molecular Weight: 2622.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Conjugation: Conjugated

Application: SARS-CoV-2 Spike Furin Cleavage Site Substrate is a synthetic peptide substrate designed to mimic the furin cleavage site targeted by the SARS-CoV-2 spike protein and related host proteases. Spike protein cleavage is an important activation step involved in viral entry, membrane fusion, and host-cell infection. This substrate is useful for monitoring spike-associated proteolytic activity and screening inhibitors that interfere with spike processing. It is widely used in virology, antiviral research, host–virus interaction studies, and SARS-CoV-2 entry mechanism analysis, supporting development of compounds targeting spike protein activation and coronavirus infection.