Product Name: [Arg(Me1)17]-Histone H3 (1-21)-GGK(Biotin)-NH2
Sequence One Letter Code: ARTKQTARKSTGGKAP-R(Me1)-KQLA-GGK(Biotin)-NH2
Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg(Me1)-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2
Molecular Weight: 2736.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Conjugated
Conjugation Type: Biotins
Code Nacres: NA.26
Application: [Arg(Me1)17]-Histone H3 (1–21)-GGK(Biotin) is a synthetic histone H3 peptide monomethylated at arginine 17, a post-translational modification associated with transcriptional activation. H3R17 methylation is linked to transcriptional coactivator recruitment, chromatin remodeling, and active chromatin states. The peptide includes a C-terminal Gly-Gly linker followed by biotinylated lysine, enabling streptavidin-based affinity capture, pull-down, and protein-binding assays. This modified histone peptide is widely used in epigenetics research to study arginine methylation, PRMT-dependent regulation, histone reader interactions, chromatin signaling, and protein recognition of activating histone marks.
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