[Arg(Me1)3]-Histone H4 (1-23)-GGK(Biotin)

Product Name: [Arg(Me1)3]-Histone H4 (1-23)-GGK(Biotin)

Sequence One Letter Code: SG-R(Me1)-GKGGKGLGKGGAKRHRKVLR-GGK(Biotin)

Sequence Three Letter Code: H-Ser-Gly-Arg(Me1)-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2843.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Arg(Me1)3]-Histone H4 (1–23)-GGK(Biotin) is a synthetic histone H4 peptide monomethylated at arginine 3, a modification catalyzed by PRMT1 and associated with transcriptional activation. H4R3 monomethylation promotes subsequent acetylation of histone H4 by p300, linking arginine methylation to chromatin relaxation and gene expression. The peptide includes a C-terminal GG linker followed by biotinylated lysine, enabling streptavidin-based pull-down, capture, and binding assays. This peptide is widely used to investigate histone modification crosstalk, arginine methylation signaling, PRMT activity, chromatin-associated protein recruitment, and transcriptional epigenetic regulation.