[Arg(Me1)3]-Histone H4(1-21)-GGK(Biotin)

[Arg(Me1)3]-Histone H4 (1–21)-GGK(Biotin) is a synthetic histone H4 peptide monomethylated at arginine 3, an epigenetic modification associated with transcriptional activation and chromatin relaxation. H4R3 monomethylation can facilitate subsequent acetylation of histone H4 tails by p300, linking arginine methylation to gene expression regulation. The peptide features an acetylated N-terminus and a C-terminal GG linker followed by biotinylated lysine, supporting affinity-based assays. It is widely used to study arginine methylation recognition, chromatin remodeling mechanisms, histone modification crosstalk, transcriptional regulation, and PRMT-related epigenetic signaling.

Product Name: [Arg(Me1)3]-Histone H4(1-21)-GGK(Biotin)

Sequence One Letter Code: Ac-SG-R(Me1)-GKGGKGLGKGGAKRHRKV-GGK(Biotin)

Sequence Three Letter Code: Ac-Ser-Gly-Arg(Me1)-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2616.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26