[Arg(Me2a)26]-Histone H3 (15-36)-GGK(Biotin)

Product Name: [Arg(Me2a)26]-Histone H3 (15-36)-GGK(Biotin)

Sequence One Letter Code: APRKQLATKAA-R(Me2a)-KSAPATGGVK-GGK(Biotin)

Sequence Three Letter Code: H-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg(Me2a)-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2704.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Arg(Me2a)26]-Histone H3 (15–36)-GGK(Biotin) is a synthetic histone H3 peptide corresponding to residues 15–36 and asymmetrically dimethylated at arginine 26, a modification catalyzed by CARM1. H3R26 asymmetric dimethylation is associated with transcriptional activation and can inhibit deimination by PADI4, highlighting crosstalk between arginine methylation and citrullination. The peptide includes a C-terminal GGK linker and biotinylated lysine, enabling affinity-based capture and binding assays. It is widely used in chromatin biology to study PRMT activity, arginine methylation, transcriptional regulation, and histone modification interplay.