[Lys(Me1)9]-Histone H3 (1-21)-K(Biotin)

Product Name: [Lys(Me1)9]-Histone H3 (1-21)-K(Biotin)

Sequence One Letter Code: ARTKQTAR-K(Me1)-STGGKAPRKQLA-K(Biotin)

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me1)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Lys(Biotin)-OH

Molecular Weight: 2623.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me1)9]-Histone H3 (1–21)-K(Biotin) is a synthetic N-terminal histone H3 peptide monomethylated at lysine 9 and biotinylated at a C-terminal lysine. H3K9 monomethylation is associated with transcriptionally silent regions in euchromatin and can serve as a precursor mark for higher methylation states. The biotin label supports affinity-based detection, pull-down, immobilization, and interaction assays. This modified histone peptide is commonly used to study histone methyltransferase activity, including Suv39h1 and Suv39h2, chromatin-binding proteins, early repressive epigenetic marks, and methylation-dependent chromatin regulation.