[Lys(Me2)79]-Histone H3 (69-89)-K(Biotin)

Product Name: [Lys(Me2)79]-Histone H3 (69-89)-K(Biotin)

Sequence One Letter Code: RLVREIAQDF-K(Me2)-TDLRFQSSAV-K(Biotin)

Sequence Three Letter Code: H-Arg-Leu-Val-Arg-Glu-Ile-Ala-Gln-Asp-Phe-Lys(Me2)-Thr-Asp-Leu-Arg-Phe-Gln-Ser-Ser-Ala-Val-Lys(Biotin)-OH

Molecular Weight: 2862.5

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me2)79]-Histone H3 (69–89)-GK(Biotin) is a synthetic histone H3 peptide spanning residues 69–89 and dimethylated at lysine 79, a modification located within the globular domain of histone H3. H3K79 dimethylation is associated with transcriptional regulation, DNA damage responses, and chromatin-associated signaling. The peptide contains a C-terminal glycine followed by biotinylated lysine, enabling affinity capture, immobilization, pull-down, and binding assays. This peptide is commonly used in epigenetics research to study DOT1L-mediated methylation, internal histone mark recognition, methyl-lysine reader interactions, DNA damage signaling, and chromatin regulation.