[Lys(Me3)4]-Histone H3 (1-21)-GGK(Biotin)-NH2

Product Name: [Lys(Me3)4]-Histone H3 (1-21)-GGK(Biotin)-NH2

Sequence One Letter Code: ART-K(Me3)-QTARKSTGGKAPRKQLA-GGK(Biotin)-NH2

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys(Me3)-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2

Molecular Weight: 2765.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me3)4]-Histone H3 (1–21)-GGK(Biotin) is a synthetic histone H3 N-terminal peptide trimethylated at lysine 4, a hallmark epigenetic mark of transcriptionally active and poised promoters. H3K4 trimethylation is associated with cell identity, lineage commitment, imprinting control regions, and transcriptional regulation. The peptide includes a C-terminal Gly-Gly linker followed by biotinylated lysine, enabling streptavidin-based capture, pull-down, and binding assays. This modified histone peptide is widely used to study chromatin reader proteins, histone mark recognition, active promoter regulation, epigenetic signaling, and mechanisms distinguishing active, poised, and repressed gene states.