Product Name: PACAP (1-38), amide, human, ovine, rat, Biotin-labeled
Sequence One Letter Code: Biotin-HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
Sequence Three Letter Code: Biotin-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Chemical Formula:C213H345N65O55S2
Molecular Weight: 4760.8
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human, ovine, rat
Conjugation: Conjugated
Conjugation Type: Biotins
Code Nacres: NA.26
Application: Biotin-labeled PACAP-38 is the full-length amidated pituitary adenylate cyclase-activating polypeptide modified with an N-terminal biotin tag for assay versatility. PACAP is a highly conserved neuropeptide closely related to vasoactive intestinal polypeptide and is a potent stimulator of adenylate cyclase activity. It regulates neurotransmission, glucose-dependent insulin secretion, neuroprotection, and immune modulation, including protection of T cells from activation-induced apoptosis. The biotin label enables immobilization, affinity capture, and receptor binding assays. Biotin-labeled PACAP-38 is widely used in neuroendocrine research, metabolic signaling studies, receptor pharmacology, and immune system investigations.
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