Product Name: SARS-inhibitor 5
Sequence One Letter Code: ATCYCRTGRCATRESLSGVCEISGRLYRLCCR-OH
Sequence Three Letter Code: Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg-OH
Chemical Formula:C144H244N50O45S6
Molecular Weight: 3588.19
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: Human lectin-like defensin-5
Conjugation: Unconjugated
Application: SARS-Inhibitor 5 is an α-defensin-derived antimicrobial peptide with antiviral activity against SARS-CoV-2. Defensins are innate immune peptides with broad antimicrobial and antiviral properties. This peptide inhibits binding of the SARS-CoV-2 spike protein to the ACE2 receptor, thereby interfering with viral entry into host cells. SARS-Inhibitor 5 is used as a research tool for studying host defense peptides, coronavirus attachment, virus–host interactions, and peptide-based antiviral strategies. It supports investigations of spike–ACE2 blockade, innate immune antiviral mechanisms, SARS-CoV-2 entry inhibition, and therapeutic approaches targeting early infection steps.
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