Thrombin Receptor Agonist (FLLRN)

Product Name: Thrombin Receptor Agonist (FLLRN)

Sequence One Letter Code: FLLRN

Sequence Three Letter Code: H-Phe-Leu-Leu-Arg-Asn-OH

Cas No: 141136-84-7

Chemical Formula:C31H51N9O7

Molecular Weight: 661.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)N

IUPAC: (2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-oxobutanoic acid

INCHIKEY: WBNIBLBGDVPFOO-LSBAASHUSA-N

INCHI:

InChI=1S/C31H51N9O7/c1-17(2)13-22(38-26(42)20(32)15-19-9-6-5-7-10-19)29(45)39-23(14-18(3)4)28(44)37-21(11-8-12-36-31(34)35)27(43)40-24(30(46)47)16-25(33)41/h5-7,9-10,17-18,20-24H,8,11-16,32H2,1-4H3,(H2,33,41)(H,37,44)(H,38,42)(H,39,45)(H,40,43)(H,46,47)(H4,34,35,36)/t20-,21-,22-,23-,24-/m0/s1

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Thrombin Receptor Agonist Peptide FLLRN is a synthetic ligand that activates protease-activated receptor 1, a G protein–coupled receptor involved in thrombin-mediated signaling. PAR-1 plays important roles in coagulation, inflammation, platelet activation, vascular biology, and cellular communication. This peptide is widely used as a pharmacological tool for studying thrombin receptor activation, downstream signal transduction, and cellular responses linked to hemostasis and inflammatory regulation. Thrombin Receptor Agonist Peptide FLLRN supports cardiovascular research, platelet function studies, immune signaling investigations, and mechanistic analysis of PAR-1-regulated biological processes.