Thrombospondin (TSP-1)-derived Peptide; binding motif for CD36

Product Name: Thrombospondin (TSP-1)-derived Peptide; binding motif for CD36

Sequence One Letter Code: CSVTCG (S-S Bonded)

Sequence Three Letter Code: H-Cys-Ser-Val-Thr-Cys-Gly-OH (S-S Bonded)

Chemical Formula:C20H34N6O9S2

Molecular Weight: 566.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Bovine

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Thrombospondin-1 CD36 Binding Motif Peptide is a cyclized, thrombospondin-1-derived peptide representing a specific binding motif responsible for interaction with the CD36 receptor. Cyclization through a disulfide bond helps mimic the native structural conformation required for receptor binding. Thrombospondin-1 is a matrix-associated glycoprotein involved in angiogenesis, tumor adhesion, platelet aggregation, and metastasis. This peptide has been shown to competitively inhibit thrombospondin–CD36 interactions, platelet aggregation, and tumor metastasis. It is widely used to study angiogenesis regulation, CD36-mediated signaling, tumor progression, anti-angiogenic mechanisms, and metastasis-related pathways.