Uroguanylin (Rat)

Product Name: Uroguanylin (Rat)

Sequence One Letter Code: TDECELCINVACTGC (Disulfide bonds between Cys4-Cys12 and Cys7-Cys15)

Sequence Three Letter Code: H-Thr-Asp-Glu-Cys-Glu-Leu-Cys-Ile-Asn-Val-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bonds between Cys4-Cys12 and Cys7-Cys15)

Chemical Formula:C60H100N16O25S4

Molecular Weight: 1569.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: rat

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Uroguanylin, Rat, is a natriuretic peptide hormone involved in sodium and water balance, especially during high dietary salt intake. Closely related to guanylin, uroguanylin activates guanylate cyclase receptors in the intestine and kidney, triggering cyclic GMP signaling that promotes sodium excretion. Originally isolated from rat urine and duodenum, it plays an important role in gut–kidney endocrine communication. Uroguanylin, Rat, is commonly used in renal physiology, gastrointestinal research, electrolyte homeostasis studies, and investigations of natriuretic signaling, cyclic GMP-mediated regulation, intestinal salt handling, and kidney-related fluid balance mechanisms.