WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist

Product Name: WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist

Sequence One Letter Code: WRWWWW

Sequence Three Letter Code: H-Trp-Arg-Trp-Trp-Trp-Trp-OH

Chemical Formula:C61H64N14O7

Molecular Weight: 1105.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Conjugation: Unconjugated

Code Nacres: NA.26

Application: WRW4 is a synthetic peptide antagonist of formyl peptide receptor-like 1, also known as FPRL1 or FPR2. It inhibits binding of the agonist WKYMVm to the receptor, making it useful for studying receptor-specific inflammatory signaling. FPRL1 is a chemoattractant receptor expressed in phagocytic cells in peripheral blood and the brain, where it contributes to immune cell migration and inflammatory responses. WRW4 is widely used in immunology, inflammation, neuroinflammation, and neurodegeneration research to investigate FPRL1-mediated signaling pathways, host defense mechanisms, chemotaxis, and modulation of immune cell activation.