[Arg(Me1)8]-Histone H3 (1-21)-K(Biotin)-NH2

Product Name: [Arg(Me1)8]-Histone H3 (1-21)-K(Biotin)-NH2

Sequence One Letter Code: ARTKQTA-R(Me1)-KSTGGKAPRKQLA-K(Biotin)-NH2

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg(Me1)-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Lys(biotin)-NH2

Molecular Weight: 2622.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Arg(Me1)8]-Histone H3 (1–21)-K(Biotin) is a synthetic histone H3 N-terminal peptide monomethylated at arginine 8 and biotinylated at a C-terminal lysine. H3R8 monomethylation is implicated in transcriptional regulation, chromatin dynamics, and modification-dependent interactions between histones and regulatory proteins. The biotin label facilitates affinity purification, immobilization, pull-down assays, and binding studies. This modified histone peptide is commonly used in epigenetics research to study arginine methylation, PRMT-related enzyme activity, protein–histone interactions, chromatin remodeler recruitment, transcription factor binding, and functional consequences of histone modification patterns.