[Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin)

Product Name: [Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin)

Sequence One Letter Code: Ac-SG-R(Me2a)-GKGGKGLGKGGAKRHRKV-GGK(Biotin)

Sequence Three Letter Code: Ac-Ser-Gly-Arg(Me2a)-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2630.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Arg(Me2a)3]-Histone H4 (1–21)-GGK(Biotin) is a synthetic histone H4 peptide asymmetrically dimethylated at arginine 3, with both methyl groups located on the same nitrogen of the arginine guanidinium group. H4R3 asymmetric dimethylation is an epigenetic mark linked to transcriptional activation and p300-mediated histone acetylation. The peptide includes a C-terminal GG linker and biotinylated lysine for affinity-based capture, pull-down, and binding assays. It is widely used to study arginine methylation, PRMT activity, chromatin remodeling, histone modification crosstalk, and transcription-associated epigenetic regulation.