Big Gastrin-1, human

Product Name: Big Gastrin-1, human

Sequence One Letter Code: Pyr-LGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF-NH2

Sequence Three Letter Code: pGlu-Leu-Gly-Pro-Gln-Gly-Pro-Pro-His-Leu-Val-Ala-Asp-Pro-Ser-Lys-Lys-Gln-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2

Cas No: 60675-77-6

Chemical Formula:C176H251N43O53S

Molecular Weight: 3849.5

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Big Gastrin-1, also known as Gastrin-34, is a major bioactive gastrin peptide secreted by gastric G cells in response to food intake. It stimulates hydrochloric acid secretion from parietal cells through activation of the CCK2/gastrin receptor and contributes to digestive regulation by promoting histamine and pepsinogen secretion. Gastrin-34 is carboxy-amidated and may be partially tyrosine-sulfated, with amidation required for effective receptor binding. This peptide is widely used in studies of gastric physiology, gastrointestinal hormone signaling, acid secretion disorders, digestive regulation, and CCK2 receptor-mediated endocrine pathways.