Biotinylated human α-CGRP is an N-terminally biotin-labeled form of the 37-amino-acid calcitonin gene-related peptide alpha isoform. Human α-CGRP is generated by tissue-specific processing of the calcitonin gene and is the predominant CGRP isoform in neural tissues. Released from sensory and motor neurons, CGRP regulates vasodilation, skeletal muscle function, nociception, and neurovascular signaling. The long-chain biotin spacer supports receptor binding studies, affinity capture, immobilization, and assay development. Biotinylated human α-CGRP is widely used in neurology, migraine research, vascular biology, receptor pharmacology, and CGRP signaling investigations.
Product Name: Calcitonin Gene Related Peptide, CGRP (alpha), human, Biotin-LC-labeled
Sequence One Letter Code: Biotin-LC-ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (Disulfide bridge:2-7)
Sequence Three Letter Code: Biotin-LC-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge:2-7)
Molecular Weight: 4128.9
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Unconjugated
Code Nacres: NA.26
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