Biotin-labeled human ghrelin is a synthetic peptide hormone modified at the N-terminus to support detection, immobilization, and receptor-binding assays. Ghrelin is a 28-amino-acid orexigenic hormone secreted mainly by gastric P/D1 cells and released during fasting to stimulate appetite and regulate energy balance. Its endogenous activity depends on n-octanoylation of Ser3, which enables high-specificity binding to growth hormone secretagogue receptor 1a. Biotin-labeled human ghrelin is widely used in metabolic and endocrine research to study appetite regulation, ghrelin receptor signaling, hormone-receptor interactions, obesity mechanisms, and energy homeostasis.
Product Name: Ghrelin, human, Biotin-labeled
Sequence One Letter Code: Biotin-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR
Sequence Three Letter Code: Biotin-Gly-Ser-[Ser(n-octanoyl)]-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH
Chemical Formula:C157H254N48O48S
Molecular Weight: 3597.4
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Conjugated
Conjugation Type: Biotins
Code Nacres: NA.26
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