Product Name: GIP (1-42)-acetate, human
Sequence One Letter Code: Ac-YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ-OH
Sequence Three Letter Code: Ac-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
Cas No: 100040-31-1
Chemical Formula:C228H341N60O68S1
Molecular Weight: 4983.59
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Unconjugated
Application: Human glucose-dependent insulinotropic polypeptide (GIP) is a full-length 42-amino-acid incretin hormone released from intestinal K cells after food intake. GIP enhances glucose-dependent insulin secretion from pancreatic β-cells and supports β-cell proliferation and survival. Beyond its insulinotropic activity, GIP is also involved in lipid metabolism, adipose tissue function, and energy storage. This peptide is widely used in metabolic, endocrine, and diabetes research to study incretin signaling, pancreatic β-cell function, gut hormone biology, obesity-related pathways, and glucose homeostasis. Human GIP is a valuable tool for investigating metabolic disease mechanisms and incretin-based therapeutic strategies.