Hyp4-Kallidin

Product Name: Hyp4-Kallidin

Sequence One Letter Code: KRPOGFSPFR

Sequence Three Letter Code: Lys-Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg

Chemical Formula:C56H85N17O13

Molecular Weight: 1204.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Conjugation: Unconjugated

Code Nacres: NA.31

Application: Hyp⁴-Kallidin is a hydroxylated form of kallidin, also known as Lys-bradykinin, generated from kininogen cleavage by tissue kallikrein. Hydroxylation of the proline residue does not significantly alter its biological activity. Hyp⁴-Kallidin acts as an agonist of the bradykinin B2 receptor and functions as a potent inflammatory mediator. It plays important roles in vasodilation, vascular permeability, pain, and acute or chronic inflammatory responses. This peptide is widely used to study kinin system regulation, B2 receptor signaling, inflammatory mechanisms, vascular biology, and peptide modifications affecting bradykinin-related activity.