[Lys(Ac)16]-Histone H4 (1-21)-GGK(Biotin)

Product Name: [Lys(Ac)16]-Histone H4 (1-21)-GGK(Biotin)

Sequence One Letter Code: Ac-SGRGKGGKGLGKGGA-K(Ac)-RHRKV-GGK(Biotin)

Sequence Three Letter Code: Ac-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2644.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Ac)16]-Histone H4 (1–21)-GGK(Biotin) is a synthetic N-terminal histone H4 peptide acetylated at lysine 16, a key epigenetic modification involved in chromatin decompaction and transcriptional activation. H4K16 acetylation induces structural changes in nucleosomes that enhance transcription factor accessibility and gene expression. The peptide includes a C-terminal GG linker and biotinylated lysine, supporting streptavidin-based pull-down, binding, and detection assays. This acetylated histone peptide is widely used in chromatin biology and epigenetics research to study acetylation-dependent protein interactions, histone reader specificity, chromatin remodeling, and transcriptional regulation.