Product Name: [Lys(Me1)36]-Histone H3 (26-46)-K(Biotin)
Sequence One Letter Code: RKAAPATGGV-K(Me1)-KPHRYRPGTV-K(Biotin)
Sequence Three Letter Code: H-Arg-Lys-Ala-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me1)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Thr-Val-Lys(BIOTIN)-OH
Molecular Weight: 2616.2
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: human
Conjugation: Conjugated
Conjugation Type: Biotins
Code Nacres: NA.26
Application: [Lys(Me1)36]-Histone H3 (26–46)-K(Biotin) is a synthetic peptide derived from Schizosaccharomyces histone H3 residues 26–46 and monomethylated at lysine 36. H3K36 methylation is closely associated with RNA polymerase II elongation, transcriptional fidelity, chromatin structure, and DNA repair processes. The biotinylated lysine supports affinity-based capture, detection, and binding assays for histone-interacting proteins. This modified histone peptide is widely used in epigenetics research to study methyl-lysine recognition, histone reader specificity, chromatin regulation, transcription-coupled signaling, DNA repair-associated chromatin mechanisms, and modification-dependent protein interactions.
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