[Lys(Me2)18]-Histone H3 (1-21)-GGK(Biotin)-NH2

Product Name: [Lys(Me2)18]-Histone H3 (1-21)-GGK(Biotin)-NH2

Sequence One Letter Code: ARTKQTARKSTGGKAPR-K(Me2)-QLA-GGK(Biotin)-NH2

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys(Me2)-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2

Molecular Weight: 2750.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me2)18]-Histone H3 (1–21)-GGK(Biotin) is a synthetic histone H3 N-terminal peptide dimethylated at lysine 18 and modified with a C-terminal Gly-Gly linker followed by biotinylated lysine. H3K18 dimethylation is associated with transcriptional regulation, chromatin accessibility, and modulation of transcription factor recruitment. The biotin tag enables affinity-based capture, pull-down, detection, and protein interaction assays. This modified histone peptide is commonly used in epigenetics research to study lysine methylation, histone-modifying enzyme specificity, methyl-lysine reader recognition, chromatin-associated protein binding, and gene expression regulation.