[Lys(Me2)36]-Histone H3 (26-46)-K(Biotin)

Product Name: [Lys(Me2)36]-Histone H3 (26-46)-K(Biotin)

Sequence One Letter Code: RKAAPATGGV-K(Me2)-KPHRYRPGTV-K(Biotin)

Sequence Three Letter Code: H-Arg-Lys-Ala-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me2)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Thr-Val-Lys(BIOTIN)-OH

Molecular Weight: 2630.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me2)36]-Histone H3 (26–46)-K(Biotin) is a synthetic histone H3 peptide dimethylated at lysine 36, a modification associated with RNA polymerase II-mediated transcriptional elongation. H3K36 dimethylation plays important roles in chromatin organization, transcriptional fidelity, and DNA repair processes. The peptide includes a biotinylated lysine at the C-terminus, enabling affinity capture, pull-down, detection, and protein interaction assays. This modified histone peptide is widely used in epigenetics research to study methyltransferase activity, methyl-lysine reader specificity, chromatin signaling, transcription-coupled regulation, and protein recognition of H3K36 methyl marks.