[Lys(Me2)9]-Histone H3 (1-21)-GGK(Biotin)

Product Name: [Lys(Me2)9]-Histone H3 (1-21)-GGK(Biotin)

Sequence One Letter Code: ARTKQTAR-K(Me2)-STGGKAPRKQLA-GGK(Biotin)

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me2)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2751.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me2)9]-Histone H3 (1–21)-GGK(Biotin) is a synthetic histone H3 N-terminal peptide dimethylated at lysine 9, a repressive epigenetic mark associated with facultative heterochromatin and gene silencing. H3K9 dimethylation plays an important role in chromatin organization, transcriptional repression, and modification-dependent protein recruitment. The peptide includes a C-terminal GG linker followed by biotinylated lysine, supporting streptavidin-based capture, pull-down, and binding assays. This modified histone peptide is widely used to study chromatin-binding proteins, methyl-lysine reader domains, histone methylation dynamics, repressive chromatin marks, and epigenetic gene regulation.