[Lys(Me3)27]-Histone H3 (21-44)-GK(Biotin)

Product Name: [Lys(Me3)27]-Histone H3 (21-44)-GK(Biotin)

Sequence One Letter Code: ATKAAR-K(Me3)-SAPATGGVKKPHRYRPG-GK(Biotin)

Sequence Three Letter Code: H-Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me3)-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2960.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Lys(Me3)27]-Histone H3 (21–44)-GK(Biotin) is a synthetic histone H3 peptide trimethylated at lysine 27, a well-known repressive chromatin mark involved in transcriptional silencing. H3K27me3 is closely linked to Polycomb repressive complex activity and regulation of developmental and cell identity genes. The peptide contains a C-terminal glycine and biotinylated lysine, enabling use in affinity-based detection, binding studies, and enzymatic assays. This modified histone peptide is widely applied in epigenetics research, including studies of chromatin remodeling, histone modification recognition, Polycomb-mediated gene repression, epigenetic inheritance, and transcriptional regulation mechanisms.