M13 Skeletal Muscle Myosin Light Chain Kinase Peptide, SK-MLCK M13

Product Name: M13 Skeletal Muscle Myosin Light Chain Kinase Peptide, SK-MLCK M13

Sequence One Letter Code: KRRWKKNFIAVSAANRFKKISSSGAL

Sequence Three Letter Code: H-Lys-Arg-Arg-Trp-Lys-Lys-Asn-Phe-Ile-Ala-Val-Ser-Ala-Ala-Asn-Arg-Phe-Lys-Lys-Ile-Ser-Ser-Ser-Gly-Ala-Leu-OH

Cas No:

Chemical Formula:C134H223N43O33

Molecular Weight: 2964.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Human, mouse, rat, bovine

Conjugation: Unconjugated

Code Nacres: NA.26

Application: M13 is a synthetic peptide corresponding to the calmodulin-binding domain of skeletal muscle myosin light chain kinase. It serves as a prototypical calmodulin target sequence and binds calmodulin in a calcium-dependent manner. Calmodulin is a ubiquitous intracellular Ca²⁺ sensor that regulates diverse enzymes, ion channels, and signaling pathways. The M13 peptide is widely used as a model ligand for studying CaM–protein interactions, calcium-dependent conformational changes, and calmodulin-mediated signal transduction. It is also valuable in biochemical assays, fluorescence studies, and structural investigations of calmodulin binding mechanisms.