Neurogranin 28-43 [AAKIQASFRGHMARKK], Biotin-LC

Product Name: Neurogranin 28-43 [AAKIQASFRGHMARKK], Biotin-LC

Sequence One Letter Code: Biotin-LC-AAKIQASFRGHMARKK

Sequence Three Letter Code: Biotin-LC-Ala-Ala-Lys-Ile-Gln-Ala-Ser-Phe-Arg-Gly-His-Met-Ala-Arg-Lys-Lys-OH

Chemical Formula:C94H159N31O20S2

Molecular Weight: 2139.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human, bovine, mouse

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: Neurogranin (28–43), Biotin-labeled, is a synthetic peptide derived from neurogranin, a naturally occurring substrate of protein kinase C. The sequence AAKIQASFRGHMARKK shows strong specificity as a PKC substrate, with a reported Km of 150 nM and minimal phosphorylation by PKA or CaMKII. Basic residues flanking the phosphorylated serine are important for substrate selectivity. The biotin label supports capture and detection in kinase assay formats. This peptide is widely used in PKC activity assays, phosphorylation studies, kinase specificity research, neuronal signaling investigations, and protein kinase inhibitor screening.