Plasmin Substrate, fluorescent (H-D-Val-Leu-Lys-AFC)

Product Name: Plasmin Substrate, fluorescent (H-D-Val-Leu-Lys-AFC)

Sequence One Letter Code: vLK-AFC

Sequence Three Letter Code: H-D-Val-Leu-Lys-AFC

Chemical Formula:C27H38F3N5O5

Molecular Weight: 569.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26

Application: Plasmin Fluorogenic Substrate is designed for sensitive detection of plasmin activity, a key serine protease responsible for fibrin clot degradation during fibrinolysis. Upon enzymatic cleavage, AFC fluorescence is released and can be measured at Abs/Em 380/500 nm. In addition to clot dissolution, plasmin contributes to wound healing, liver regeneration, extracellular matrix remodeling, and tissue repair processes. This peptide substrate is widely used in coagulation research, fibrinolysis assays, thrombolysis studies, enzymatic profiling, protease kinetics, and screening of plasmin-targeted inhibitors for cardiovascular and hemostasis-related research.