PMAP-23

Product Name: PMAP-23

Sequence One Letter Code: RIIDLLWRVRRPQKPKFVTVWVR

Sequence Three Letter Code: H-Arg-Ile-Ile-Asp-Leu-Leu-Trp-Arg-Val-Arg-Arg-Pro-Gln-Lys-Pro-Lys-Phe-Val-Thr-Val-Trp-Val-Arg-OH

Chemical Formula:C140H229N43O28

Molecular Weight: 2962.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: porcine

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Porcine Myeloid Antimicrobial Peptide-23 (PMAP-23) is a cathelicidin-derived host defense peptide with potent antimicrobial activity. It exhibits strong bactericidal effects against Gram-negative and Gram-positive bacteria and also shows antifungal activity against yeast and mold. PMAP-23 disrupts microbial membranes through electrostatic and hydrophobic interactions while displaying low toxicity toward eukaryotic cells. This peptide is widely studied as a model antimicrobial peptide in innate immunity research. PMAP-23 is used to investigate membrane-active peptide mechanisms, microbial killing, host defense responses, antifungal activity, and the development of novel antimicrobial strategies.