Ryanodine receptor 1 (RyR1) (3614-3643); Calmodulin Binding Peptide (CaMBP)

Product Name: Ryanodine receptor 1 (RyR1) (3614-3643); Calmodulin Binding Peptide (CaMBP)

Sequence One Letter Code: KSKKAVWHKLLSKQRRRAVVACFRMTPLYN

Sequence Three Letter Code: H-Lys-Ser-Lys-Lys-Ala-Val-Trp-His-Lys-Leu-Leu-Ser-Lys-Gln-Arg-Arg-Arg-Ala-Val-Val-Ala-Cys-Phe-Arg-Met-Thr-Pro-Leu-Tyr-Asn-OH

Chemical Formula:C163H272N52O37S2

Molecular Weight: 3616.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human, mouse, rat, bovine, pig

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Ryanodine Receptor 1 CaM-Binding Peptide corresponds to amino acids 3614–3643 of ryanodine receptor 1, a major intracellular calcium release channel in muscle cells. This region functions as a calmodulin-binding sequence and plays an important role in regulating calcium-induced calcium release. RyR1 activity is central to excitation–contraction coupling, skeletal muscle physiology, and intracellular calcium homeostasis. This peptide is widely used in studies of calcium signaling, calmodulin interactions, RyR1 regulation, muscle contraction mechanisms, and cell signaling pathways involving calcium-dependent protein interactions and channel modulation.