Steroid Receptor Coactivator-1, SRC-1 (686-700)

Product Name: Steroid Receptor Coactivator-1, SRC-1 (686-700)

Sequence One Letter Code: RHKILHRLLQEGSPS

Sequence Three Letter Code: H-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH

Chemical Formula:C77H131N27O21

Molecular Weight: 1771.2

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Human, pig, mouse, bovine, rat

Conjugation: Unconjugated

 Code Nacres: NA.26

Application: SRC-1 NR Box II Peptide corresponds to amino acids 686–700 of steroid receptor coactivator-1 and contains the second LXXLL motif, also known as nuclear receptor box II. SRC-1 is a transcriptional coactivator that enhances ligand-dependent gene activation by nuclear hormone receptors. This peptide is widely used to study nuclear receptor signaling, coactivator recruitment, hormone-dependent transcription, and protein–protein interactions. SRC-1 NR Box II Peptide is especially valuable for investigating how nuclear receptors recognize LXXLL motifs and how coactivator binding regulates gene expression in endocrine, cancer, and transcriptional research.