Adeno-Associated Virus Epitope 2 (AAV2)

AAV2 Epitope 2 is an immunodominant CD8⁺ T-cell peptide derived from the capsid of adeno-associated virus serotype 2. Capsid-specific cellular immune responses have been linked to hepatocyte killing and liver toxicity observed in clinical gene therapy trials involving systemic AAV2 delivery, including hemophilia studies. This peptide is widely used in gene therapy and immunology research to study vector-induced immune recognition, capsid antigen presentation, T-cell activation, and immune responses that may influence long-term transgene expression. AAV2 Epitope 2 supports safety-focused evaluation of AAV-based therapeutic platforms.

Product Name: Adeno-Associated Virus Epitope 2 (AAV2)

Sequence One Letter Code: VPQYGYLTL

Sequence Three Letter Code: H-Val-Pro-Gln-Tyr-Gly-Tyr-Leu-Thr-Leu-OH

Chemical Formula:C51H76N10O14

Molecular Weight: 1053.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: AAV

Conjugation: Unconjugated

Code Nacres: NA.26