Argireline

Product Name:Argireline

Form:Acetate salt

CAS No:616204-22-9

Molar Mass:888.99

Purity:95%

Chemical Formula:C34H60N14O12S

Synonyms:(4S)-4-acetamido-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Storage:-20°C

Sequence:Ac-EEMQRR-NH2

Application:

Argireline is a powerful anti-aging peptide that reduces the appearance of fine lines and wrinkles by inhibiting facial muscle contractions. Functioning similarly to Botox but without injections, it blocks neurotransmitter release, preventing excessive muscle movement that leads to expression lines. Clinically proven to enhance skin elasticity and hydration, Argireline is widely used in anti-wrinkle creams, serums, and skincare formulations. Ideal for targeting crow’s feet, forehead lines, and nasolabial folds, it promotes a smoother, more youthful complexion. This non-invasive peptide is a key ingredient in advanced cosmetic formulations for anti-aging and skin-rejuvenation benefits.

Current Research:

Argireline has become a popular ingredient in anti-aging skincare products due to its ability to mimic the effects of botulinum toxin (Botox) without the need for injections. Research on Argireline’s mechanisms and efficacy continues to provide insights into its potential as a non-invasive anti-aging solution.

A study published in International Journal of Cosmetic Science (2023) explored the effects of Argireline in reducing facial wrinkles. Participants who used a cream containing 10% Argireline for 30 days showed a significant reduction in wrinkle depth, particularly around the eyes and forehead, where facial muscles are more active. The study concluded that Argireline could effectively reduce fine lines and wrinkles by limiting muscle contractions, which typically lead to wrinkle formation over time. The results suggested that Argireline has a similar, though milder, effect as Botox in reducing visible signs of aging.

Another study published in Journal of Cosmetic Dermatology (2024) focused on the safety and long-term use of Argireline in various formulations. The research found that while Argireline was generally well-tolerated by users, some individuals experienced mild irritation, especially when used in higher concentrations. However, the side effects were minimal and transient, making Argireline a safer alternative to invasive treatments like Botox.

Further clinical trials are investigating Argireline's ability to improve skin elasticity and overall facial appearance when combined with other ingredients like hyaluronic acid or retinol. The growing body of evidence indicates that Argireline can be an effective anti-aging treatment for individuals seeking smoother skin and a more youthful appearance without undergoing invasive procedures.

Reference:

Wang, Y., Wang, M., Xiao, X. S., Huo, J., & Zhang, W. D. (2013). The anti-wrinkle efficacy of Argireline. Journal of Cosmetic and Laser Therapy, 15(4), 237-241.