[Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin)

Product Name: [Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin)

Sequence One Letter Code: ARTKQTA-R(Me2s)-KSTGGKAPRKQLA-K(Biotin)

Sequence Three Letter Code: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg(Me2s)-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Lys(Biotin)-OH

Molecular Weight: 2637.3

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Arg(Me2s)8]-Histone H3 (1–21)-K(Biotin) is a synthetic N-terminal histone H3 peptide symmetrically dimethylated at arginine 8 and biotinylated at a C-terminal lysine. Symmetric dimethylation at Arg8 is an important epigenetic modification that influences chromatin structure and can inhibit G9a-mediated methylation of Lys9. The biotin tag enables affinity-based capture, pull-down, binding, and enzyme specificity assays. This modified histone peptide is widely used to study histone modification crosstalk, arginine methylation-dependent signaling, chromatin-binding proteins, reader protein specificity, and epigenetic mechanisms controlling transcriptional regulation.