Bac2A is a linear antimicrobial peptide derived from bovine bactenecin, a cationic host defense peptide found in neutrophils. In Bac2A, the cysteine residues responsible for disulfide bond formation in native bactenecin are replaced with alanine, producing a linear structure while retaining potent antimicrobial activity. Bac2A exhibits broad-spectrum effects against Gram-positive and Gram-negative bacteria by interacting with microbial membranes. This peptide is widely used in innate immunity research, antimicrobial mechanism studies, membrane–peptide interaction analysis, and development of peptide-based anti-infective agents targeting resistant bacterial pathogens and host defense pathways.
Product Name: Bac2A; Bactenecin 2A
Sequence One Letter Code: RLARIVVIRVAR-NH2
Sequence Three Letter Code: H-Arg-Leu-Ala-Arg-Ile-Val-Val-Ile-Arg-Val-Ala-Arg-NH2
Chemical Formula:C63H121N25O12
Molecular Weight: 1420.9
Purity: ≥ 95%
Form: Lyophilized
Storage Conditions: - 20 °C
Source / Species: Bovine
Conjugation: Unconjugated
Code Nacres: NA.26
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