BDC2.5 Mimotope 1040-31

Product Name: BDC2.5 Mimotope 1040-31

Sequence One Letter Code: YVRPLWVRME

Sequence Three Letter Code: H-Tyr-Val-Arg-Pro-Leu-Trp-Val-Arg-Met-Glu-OH

Chemical Formula:C63H97N17O14S1

Molecular Weight: 1348.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: mouse

Conjugation: Unconjugated

Code Nacres: NA.26

Application: BDC2.5 Mimotope 1040-31, also known as p31, is a strongly agonistic peptide recognized by the diabetogenic T-cell clone BDC2.5. This mimotope specifically stimulates BDC2.5 T-cell receptor transgenic T cells and elicits robust cellular immune responses. BDC2.5 Mimotope 1040-31 is widely used in type 1 diabetes research to study autoreactive T-cell activation, antigen recognition, pancreatic β-cell destruction, and immune mechanisms driving autoimmune diabetes. This peptide is valuable for investigating T-cell-mediated autoimmunity, immune tolerance, pathogenic T-cell populations, and therapeutic strategies aimed at modulating autoimmune responses.