Beta-Amyloid (1-42), HiLyte™ Fluor 488-labeled

Product Name: Beta-Amyloid (1-42), HiLyte™ Fluor 488-labeled

Sequence One Letter Code: HiLyte Fluor™ 488-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Sequence Three Letter Code: Hilyte™ Fluor488-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

Molecular Weight: 4870.8

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26

Application: HiLyte™ Fluor 488–labeled β-Amyloid (1–42) is a fluorescent amyloid peptide strongly associated with senile plaque formation in Alzheimer’s disease. Compared with Aβ (1–40), Aβ (1–42) shows higher aggregation propensity and is considered a major species in neuronal amyloid deposits. The HiLyte™ Fluor 488 label, with Abs/Em 503/528 nm, provides brighter fluorescence than FAM-labeled analogs, enabling sensitive visualization of amyloid aggregation, cellular localization, and fibrillization. This peptide is widely used in neurodegeneration research, amyloid inhibitor screening, drug discovery, and studies of Alzheimer’s disease-related plaque formation.