Beta-Amyloid (11-25)

Product Name: Beta-Amyloid (11-25)

Sequence One Letter Code: EVHHQKLVFFAEDVG

Sequence Three Letter Code: H-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-OH

Chemical Formula:C81H119N21O23

Molecular Weight: 1755.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: Beta-Amyloid (11–25) is a synthetic peptide fragment encompassing residues 11–25 of the β-amyloid protein. This region readily forms well-organized amyloid fibrils in vitro that resemble pathogenic amyloid structures observed in amyloidosis. Structural studies show that Beta-Amyloid (11–25) rapidly assembles into antiparallel β-sheet-rich aggregates, with aggregation kinetics accelerated by preformed dimers. This peptide is commonly used to investigate amyloid self-assembly, fibril formation, aggregation kinetics, and structure–aggregation relationships. It serves as a simplified model system for studying amyloidogenic processes relevant to Alzheimer’s disease and other neurodegenerative disorders.