Biotin-Exendin 4

Product Name: Biotin-Exendin 4

Sequence One Letter Code: Biotin-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

Sequence Three Letter Code: Biotin-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Chemical Formula:C194H296N52O62S2

Molecular Weight: 4413.1

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: Gila

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: Biotin-Exendin-4 is a modified form of Exendin-4 featuring an N-terminal biotin label for affinity-based detection and receptor-binding assays. Exendin-4 is a potent glucagon-like peptide-1 receptor agonist that stimulates glucose-dependent insulin secretion after nutrient intake. Originally derived from Heloderma suspectum, Exendin-4 shows greater stability and prolonged biological activity compared with native GLP-1. The biotin label enables immobilization, capture, and assay development for GLP-1 receptor studies. Biotin-Exendin-4 is widely used in incretin biology, diabetes research, metabolic regulation studies, receptor pharmacology, and ligand–receptor interaction analysis.