Caspase 3 (Apopain) Substrate 1f-z, fluorogenic

Product Name: Caspase 3 (Apopain) Substrate 1f-z, fluorogenic

Sequence One Letter Code: Z-DEVD-AFC

Sequence Three Letter Code: z-Asp-Glu-Val-Asp-AFC

Chemical Formula:C36H38F3N5O14

Molecular Weight: 821.7

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C Protected from light

Conjugation: Conjugated

Conjugation Type: Fluorescent dyes

Code Nacres: NA.26

Application: Caspase-3/7 Fluorogenic Substrate is designed for sensitive detection of caspase-3 and caspase-7 activity, two central executioner enzymes in apoptosis. Upon enzymatic cleavage, the AFC fluorophore, 7-amino-4-trifluoromethylcoumarin, is released to generate strong fluorescence measurable at excitation 370–390 nm and emission 500–510 nm. This substrate is widely used in apoptosis assays, programmed cell death research, drug screening, and biochemical analysis of caspase activation. Caspase-3/7 Fluorogenic Substrate supports quantitative detection of apoptotic signaling in cellular and enzymatic systems, making it valuable for oncology and cell biology studies.