[Cit26]-Histone H3 (21-44)-GGK(Biotin)

Product Name: [Cit26]-Histone H3 (21-44)-GGK(Biotin)

Sequence One Letter Code: ATKAA-Cit-KSAPATGGVKKPHRYRPG-GGK(Biotin)

Sequence Three Letter Code: H-Ala-Thr-Lys-Ala-Ala-Cit-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Gly-Lys(Biotin)-OH

Molecular Weight: 2975.6

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Conjugated

Conjugation Type: Biotins

Code Nacres: NA.26

Application: [Cit26]-Histone H3 (21–44)-GGK(Biotin) is a synthetic histone H3 peptide containing citrullination at arginine 26, generated by PADI4-mediated deimination. Citrullination at this site blocks CARM1-dependent arginine methylation and is associated with transcriptional repression, making this peptide useful for studying antagonistic histone modifications. The peptide includes a C-terminal GGK linker and biotinylated lysine for streptavidin-based pull-down, binding, and interaction assays. [Cit26]-Histone H3 is widely used in epigenetics research to investigate histone citrullination, modification crosstalk, chromatin signaling, and gene expression regulation.