ClearPoint™ beta-Amyloid (1-42), 13C, 15N-labeled at Arg & Lys – 50 µg

Product Name: ClearPoint™ beta-Amyloid (1-42), 13C, 15N-labeled at Arg & Lys - 50 µg

Sequence One Letter Code: DAEF-R*-HDSGYEVHHQ-K*-LVFFAEDVGSN-K*-GAIIGLMVGGVVIA [R*=R(U-13C6, U-15N4) & K*=K(U-13C6, U-15N2)]

Sequence Three Letter Code: H-Asp-Ala-Glu-Phe-Arg*-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys*-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys*-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH [Arg*=Arg(U-13C6, U-15N4) and Lys*=Lys(U-13C6, U-15N2)]

Chemical Formula:C199H307N53O59S

Molecular Weight: 4540.4

Purity: ≥ 95%

Form: Lyophilized

Storage Conditions: - 20 °C

Source / Species: human

Conjugation: Unconjugated

Code Nacres: NA.26

Application: ClearPoint™ Beta-Amyloid (1–42) is a heavy-isotope-labeled form of full-length amyloid-β peptide, with all arginine and lysine residues uniformly labeled with ¹³C and ¹⁵N. This isotopic enrichment makes the peptide especially suitable for mass spectrometry and NMR-based structural, kinetic, and quantitative studies. ClearPoint™ Beta-Amyloid (1–42) is widely used as an internal standard or tracer in Alzheimer’s disease research focused on amyloid aggregation, clearance, metabolism, and peptide quantification. It supports high-precision analyses of amyloid dynamics, neurodegeneration mechanisms, and therapeutic strategies targeting Aβ pathology.