Product Name: Decapeptide-10 (CG-Keramin2)
Purity: 95%
Storage: Keep in dark and cool dry place -5~8 degree Celsius
Application:
Decapeptide-10 (CG-Keramin2) is a biomimetic peptide designed to support healthy-looking skin and scalp through targeted reinforcement of structural proteins. Composed of ten amino acids, it is widely used in cosmetic research exploring improved hair strength, enhanced follicle vitality, and overall scalp resilience. In skincare applications, Decapeptide-10 helps promote smoother texture and supports barrier integrity by encouraging optimal cellular function. Its excellent stability and water solubility make it suitable for serums, scalp treatments, and advanced hair-care formulations aimed at strengthening, revitalizing, and improving the appearance of stressed or weakened skin and hair.
Current Research:
Decapeptide-10 (CG-Keramin2): Current Cosmetic Research & Positioning
Decapeptide-10, also known by the trade name CG-Keramin2, is a synthetic peptide composed of ten amino acids, originally designed from sequences related to keratinocyte growth factor (KGF). It is now recognized as a multifunctional cosmetic peptide with two key application areas:
Anti-aging and skin revitalization
Hair growth support and follicle strengthening
Decapeptide-10 is often described as a DKK-1 (Dickkopf-1) modulating peptide. DKK-1 is a protein associated with inhibition of hair growth and disturbance of Wnt signaling in hair follicles. By down-regulating or inhibiting DKK-1 at the cosmetic level, Decapeptide-10 is proposed to:
Promote proliferation and migration of new hair cells
Support a healthier hair growth environment
Help maintain stronger hair follicles and hair shafts
In skin, Decapeptide-10 has been linked to stimulation of fibroblast and keratinocyte proliferation, which underpins many of its anti-aging and skin-repair claims.
In topical skincare, Decapeptide-10 is positioned as a rejuvenating and smoothing peptide:
It encourages the generation of new dermal cells, helping the skin look fresher and more vital.
By supporting fibroblast activity, it contributes to better extracellular-matrix maintenance, which in turn can soften the look of fine lines and wrinkles.
Improved keratinocyte turnover helps refine skin texture, making the surface appear more even and radiant.
Supplier and technical datasheets typically highlight visible benefits such as:
Reduced appearance of fine lines and early wrinkles
Smoother, more refined skin surface
Brighter, more uniform-looking tone in “problem areas” (dull or rough zones)
Because it targets both fibroblasts (dermis) and keratinocytes (epidermis), Decapeptide-10 fits nicely into “total skin renewal” or “multi-layer anti-aging” concepts.
Decapeptide-10 is especially active in hair care:
It penetrates to the base of the hair follicles, where it supports stromal cell proliferation and hair matrix activity.
By modulating DKK-1 and supporting a favorable growth environment, it helps promote anagen (growth phase) and can assist in reducing hair shedding from cosmetic causes.
It is frequently described as strengthening both follicles and hair shafts, leading to hair that appears thicker, stronger, and more resilient.
Formulas using Decapeptide-10 commonly claim:
Stimulation of hair growth or support of natural hair density
Reinforcement of weakened or miniaturized follicles
Improved hair fiber strength and reduced breakage
This makes the peptide a popular choice in scalp serums, anti-hair-loss shampoos, intensive ampoules and leave-on tonics.
A major advantage of Decapeptide-10 is its dual functionality. The same peptide can:
Rejuvenate facial skin by boosting dermal and epidermal renewal
Strengthen hair and improve scalp condition in hair-care products
For brand owners, this allows a unified story across face care, scalp care, and hair density lines, emphasizing cellular renewal and follicle vitality.
Based on current technical literature and in vitro data, Decapeptide-10 can be positioned around the following cosmetic benefits:
For skin:
Supports the generation of new dermal cells
Reduces the appearance of fine lines and early wrinkles
Improves texture, smoothness, and radiance
Helps skin look more energized and youthful
For hair & scalp:
Promotes the proliferation of new hair cells
Strengthens hair follicles and hair shafts
Helps maintain a healthier scalp environment
Contributes to fuller, stronger, more resilient-looking hair
Decapeptide-10 is typically supplied as a white powder with high purity, suitable for water-based systems:
Water-soluble and compatible with serums, essences, gels, and emulsions
Commonly stored under cool, dry conditions to maintain stability
Often used in combination with other hair peptides (for example, Wnt-activating peptides or BMP blockers) and with classic anti-aging actives like niacinamide, panthenol, and botanical extracts
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